CoQ 10
Ubiquinone vs. Ubiquinol
CoQ 10 was initially discovered in 1957, when some very smart scientists were studying theses little cellular structures in the human body called mitochondria. It turns out that these little guys (the mitochondria not the scientists) are the power houses of the body producing most of the Adenosinetriphosphate (ATP) which is the primary source of energy for your whole body. Pretty important stuff, right! Further research showed that there were two forms of CoQ 10 (nothing is simple in the human body), Ubiquinone & Ubiquinol. It was soon determined that Ubiquinol was the active form of this enzyme and if you're looking to supplement, should be the only one to be taken as a supplement (I'll tell you why in a second). As luck would have it, the scientists, at that time, were not able to formulate a stable form of the Ubiquinol, but were able to formulate a stable form of Ubiquinone. Fifty years later a research team in Japan finally made the breakthrough that allows formulating and packaging the active form of CoQ 10.
So, what is the difference between these two forms of CoQ 10? It turns out that there is a very big difference between the two. First of all, there is this little "dance" going on in your body, wherein these two forms of CoQ 10 constantly go back and forth from one form to the other. This is not unusual, there are many chemicals in your body that do the exact same thing. What exactly is happening is this.
Ubiquinone is the oxidized form of CoQ 10. Ubiquinol is the "un-oxidized" or reduced, active form of CoQ 10. The only difference (and chemically & functionally, it is a huge difference) is that Ubiquinol has an extra hydrogen atom attached to it. This may not seem like a "big deal" to you, but to your body it is the difference between a sleeping molecule and an awake one; an inactive one and an active one.
So why in CoQ 10 important?
That's a dumb question. So why did I ask it? So that I could answer it of course!
CoQ 10 is what is called a co-enzyme. That means it is a helper enzyme that catalyzes (that's scientific talk for "helps happen") the chemical reaction that allows ATP (that's the abbreviation for that great big word above) to be formed and this allows your body to function normally. Simply put, it gives you energy. For example the reaction would look something like this:
xyz + abc = ATP. This reaction would not take place without CoQ 10 being at the level of the + sign. (I hope that didn't confuse you).
So the title of this article is "Do You Need CoQ 10?"
It could also be, "Why Supplement at all with CoQ 10?"
When you are a young pup, you're body can manufacture CoQ 10. However, (there's always a however) as you age, even starting as young as your 20's, your body gradually loses it's ability to continue to manufacture this vital co-enzyme. After the age of 40, everyone should be taking CoQ 10.
What parts of the body need CoQ 10 the most? Now that's a good question.
The larger body organs that have the largest energy requirements like the Brain, Liver, Heart, Kidneys, Skeletal Muscle & the all important Immune System require large amounts of ATP and therefore CoQ 10.
That's great, but what does it do for your body? Another good question. Lets list the benefits per organ in the body.
Heart: Coronary artery disease, angina pectoris, Congestive Heart Failure
Brain: Parkinsonism, ALS (Lou Gehrig's Disease), Huntington's Chorea
Diabetes: Helpful in type-2 diabetes mellitus
Liver: Aids in the proper functioning of the liver
Kidneys: Keeps the kidneys functioning properly
Skeletal Muscle: These are the muscles in your legs, arms, trunk, etc. and obviously require a large energy supply
Immune System: A very important part of your body, which helps fight off infections and other diseases
Now that you know what CoQ 10 does for you, you can understand the importance of taking CoQ 10 supplements. The question is which one? The answer is Ubiquinol. Why?
Because Ubiquinone is poorly absorbed into your bloodstream
Ubiquinol is readily absorbed & assimilated into your bloodstream
How much better? ............8 times better! What does that mean?
Follow this scenario.
The proper dosage of Ubiquinol is 100 mg. per day (2 gel caps) ... (although one may take as many as 6 per day). It would take 800 mg. of Ubiquinone to equal 100 mg. of Ubiquinol
That's 2 gel caps of Ubiquinol CoQ 10 vs. 16 capsules of Ubiquinone
Because Ubiquinone, prior to being absorbed into the body, has to be converted to Ubiquinol in the cells in the intestinal wall (for you scientific types, these cells are called, intestinal enterocytes), this limit's the amount of Ubiquinone that can be absorbed causing only about 2-3% of orally ingested Ubiquinone to be absorbed into your body.
Ubiquinol, because it does not have this "rate limiting" step of having to be converted into another substance prior to being absorbed, is absorbed into your body much more readily and stays in the blood stream longer.
So you can conclude that Ubiquinol has much higher Bioavailability....
Because Ubiquinol is Lipophilic (lipid soluble & water insoluble) it is more readily absorbed in the presence of fat...so....take your CoQ 10 together with Omega 3 for better blood levels and better results.
Cholesterol lowering drugs (Statins) have the effect of lowering the amount of CoQ 10 in your body leading to the possibility of many unpleasant side effects. Therefore, everyone who is taking a statin drug must also take CoQ 10.
Additionally, being as Ubiquinol is the active form of CoQ 10...Ubiquinone, once it has been absorbed into your body, has to be converted to Ubiquinol before it can become useful in your body. This is a long and not so effective process.
The simple choice is that the more effective product to take as a supplement is obviously Ubiquinol.
The bottom line is this:
WIN CoQ 10 is:
1. Absorbed into your body better
2. Keeps higher levels in your body longer
3. Is essential to good health...especially in those over 40
4. Is essential in the production of ATP
5. Is a potent antioxidant
Lastly, where can you find the new Ubiquinol CoQ 10?
Here is a link to follow to find this product: http//:RoblinWellnessToday.com
Don't forget to enter your Preferred Customer Code: Wellness2440.
To Your Good Health,
Dr. Bob
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