I'm a big proponent of resveratrol supplements. I think they're the best thing. I've been bending my family's ears about it for about a year now, but I had never talked to my mother-in-law about it. I don't usually get into her business that much, however she's struggled with her weight a bit in recent years (although I'd say that to her face) and seemed to be losing a bit of her usual vigor last time I saw her.
Not so today. After getting my regular serving of "advice" from her the conversation had warmed up a bit. I asked her if she knew about resveratrol, and if so, would she be open to taking resveratrol supplements. She got a little 'animated' and then launched into one of her stories.
Do I know about resveratrol supplements? Let me tell you what I know about resveratrol supplements. I'm going down the stairs to the subway last week and, you know, it's crowded. I'm waiting there on the platform and there's this... lady, you know. So she's making herself up, fluffing herself all over her face with powder. Finally she's finished. She puts her case away and then pulls out a stick of gum. It was Arrowmint, possibly Juicy Fruit. I don't know. She bends it onto her tongue and starts chewing, real polite like. Then she takes it out again. She puts it in a tissue, and now she's taking out another bottle.
I'm looking at her all this time and I can't stand it. I say to her, "Excuse me. What are you doing?" "I'm taking my resveratrol. Who are you?" "My name is Florence. Resvera what?" "ResveraTROL. Mind your own business Florence. Look, your train is coming!" And so it was. How did she know that? Well, I got home and asked Pearl's little boy Anthony to find out what resveratrol was for me on the internet. It's an anti-aging supplement Andrew! I bought myself a bottle of resveratrol!
I told Flo I was "happy" she was going to be with us even longer. Piecing together the chain of events that led to even my mother-in-law finding out about. and then becoming a consumer of resveratrol supplements, made me realize just how much awareness of Resveratrol has steadily grown over the last five years or so. Researchers have been publishing papers on resveratrol research since 1991, but was in 2006 when David Sinclair and Joseph Bauer published their research paper in the scientific journal Nature that excitement over resveratrol really started to build.
Then TV magazines got a hold of the story, did their profiles on Sinclair and catapulted Resveratrol into the popular awareness. Any why not? Resveratrol has a story unlike any other health product on the market. When taken in sufficient concentration, it activates a normally silent gene called the Sirtuin gene. The 'turning on' of the Sirtuin gene triggers a survival mechanism in humans, the result of which is the activation of the body's natural genetic defenses against diseases. What kind of natural genetic defenses are we talking about? Well quite a few, and in the most lethal of diseases.
Diabetes: Resveratrol improves the ability of diabetes sufferers to break down and use sugar, lowering their blood glucose level.
Cardiovascular Disease: Resveratrol lowers the levels of free radicals in arterial endothelial cells (cells that line the arteries) and prevents arterial plaque, that hardens arteries, from forming.
Cancer: Resveratrol targets specific proteins that necessary in the formation of cancer cells and also destabilizes the process leading to cancer cells forming.
Alzheimer's Disease: Resveratrol interferes with the ability of amyloid-beta, the protein that causes neuron degeneration in Alzheimer's Disease, to accumulate, as well as reducing the toxicity in the amyloid-beta that has already accumulated.
Obesity: Resveratrol reduces fat mass by signaling to fat cells to stop accumulating fat, and to shed the fat that has already accumulated.
And if you aren't suffering from any disease, Resveratrol still:
increases your energy by inducing 'mitochondrial biogenesis', which results in more ATP (the molecule that produces energy) being produced
is a high powered antioxidant helping keep the body clean and making exercise easier.
It's no wonder then, with all this going for it, that resveratrol supplements have appeared on the market and are being promoted quite heavily. But all is not well on the resveratrol supplement front. Unfortunately, the public excitement over resveratrol has been exploited to a certain degree by some supplement vendors. The result has been products being promoted as resveratrol that are in fact a low quantity of resveratrol combined with a cocktail of other ingredients, free trial offers with autoship programs that are very difficult to cancel out of, companies with very bad customer service (or no customer service at all), deceptive marketing, and more.
The con artists will be found out and eliminated from the marketplace soon enough, they are not my main concern. The most important question about resveratrol supplements, I believe, is how much resveratrol should you take? Well, that really deserves a discussion all of it's own, but if we are to follow the lead of those who really would know, it would be instructive to see what the people researching resveratrol "do" when it comes to taking supplements.
David Sinclair has indicated in a couple of interviews that he takes resveratrol. This itself is very heartening. But how much does he take? He hasn't directly said (as Harvard Medical School doesn't allow him to), but he has indicated he takes a dosage of 5mgs per kg of body weight per day. That puts his daily resveratrol dosage at about 315 mgs per day. If you want to emulate his intake for yourself, multiply your body weight in kilograms by 5 mgs and you will have your daily serving. The average person will end up between 300 and 500 mgs per day.
So you're a bit on the heavy side and after doing that calculation you are a little worried about taking too much? Take heart, research has been done with human subjects showing daily resveratrol dosages as high as 9000 mgs cause no adverse side effects. The only signs of toxicity showed up when the daily dose of resveratrol was 10,000 mgs. I conveyed this fact to my mother-in-law, trying to gently suggest she could probably afford to buy a more potent supplement formulation than the one she had. "I'm very happy with my resveratrol Andrew... Thank you!". It comes in the mail every month." What can you do? At least has her spark back.
Resveratrol supplements are here to stay, the benefits are too many and too profound for resveratrol to ignored or for it to go away. Let's face it, if the whole story hooked Flo, well, I think you should look into including them in your daily supplement regime too.
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